Can Egg Donation Trigger Infertility

Egg donation is critical, particularly within the case of early ovarian failure, a big danger of genetic illness, and broken oocytes.

Can egg donation be harmful for the donor regardless of being a real reward for the recipient?

Let’s learn extra to seek out out.

The infertility dangers throughout the stimulation interval 

follicule stimulation

The method of donating eggs begins with ovulation stimulation

Ovulation might be induced in a number of follicles on the identical time utilizing hormone injections, whereas it happens naturally in a single follicle. 

As a result of every girl reacts in another way to the stimulation, the primary danger related to the oocytes comes into play right here.

 The first hazard is overstimulation. Throughout this time, the egg donor undergoes common ultrasound scans to evaluate the dimensions and variety of maturing follicles. In instances of overstimulation, the ache is continuously extreme, and problems might necessitate hospitalization. 

Good monitoring, however, significantly reduces this danger, and full information of this attainable aspect impact of the stimulation interval retains medical doctors alert and completely able to managing hyperstimulation. 

The dangers related to the puncture


As soon as The follicles are mature, and ovulation has occurred; the oocytes should now be extracted. A small surgical intervention is required to insert a probe and a “vacuum” to gather the oocytes. 

Even when the operation is just a few minutes lengthy, it nonetheless necessitates some native anaesthesia or hypnosis and carries the identical dangers as some other operation, regardless of how minor: ovarian abscess, vaginal bleeding. All of this heals extraordinarily properly.

Slight infertility dangers of egg donation

egg donation infertility risks

Usually, the donor’s signs from the hormone drug are minimal and much like or barely extra intense than these skilled throughout menstruation.

This ovarian stimulation drug is self-administered by the donor herself by way of subcutaneous injections into the stomach. The commonest negative effects are the next:

  • Modifications in temper or character.
  • Slight swelling and / or discomfort within the stomach space attributable to punctures.
  • Slight improve in physique weight.
  • Legs are just a little heavy.
  • Vaginal dryness.
  • Fatigue.

Suggestions for egg donors to keep away from infertility


It’s regular to have many doubts initially of the egg donation course of. It’s essential {that a} specialist focus on the potential advantages and downsides of the donation and tackle the entire future donor’s issues.

The donation course of have to be began with absolute conviction and resolution on the a part of the donor.

As soon as hormonal stimulation has begun, it’s important that the donor inform the medical workers of the signs she is experiencing throughout remedy.

The knowledge can forestall critical penalties reminiscent of the event of hormonal issues. For that reason, professionals insist that donors come to the clinic in case of extreme signs or intense discomfort.

Can egg donation trigger infertility?

egg donation

It doesn’t. The never-ending ovarian cycle follows a lady all through her life, even earlier than she has menstruation. 

About three months earlier than the 14-day cycle, often known as the menstrual cycle, begins, the lady prompts a few of the hundreds of dormant microscopic follicles in her ovary (primordial follicles). These activated follicles grow to be antral follicles, which is able to have interaction in a fierce battle for ovulation.

All, or almost all, antral follicles are stimulated by ovarian stimulation in order that they’ll mature and be extracted by way of puncture. Aside from one, all of those oocytes would have been drawn right into a pure cycle.

Subsequently, IVF and egg donation don’t trigger early menopause, simply as taking contraceptives doesn’t make it seem later.

Does egg donation shorten a lady’s fertility interval?


Donating eggs doesn’t cut back a lady’s fertility. A girl is born with a set variety of eggs, that are misplaced with every cycle. Only some are helpful, that are mature, whereas the remainder are naturally eradicated.

Just one egg cell matures (generally extra) throughout a fertile girl’s menstrual cycle, in comparison with quite a few oocytes (10-20) that may naturally degenerate. 

The remedy for egg donation is to stimulate the donor’s ovaries with hormonal medicine, inflicting extra follicles to develop and thus mature into extra eggs that may in any other case be misplaced attributable to atresia.

Thus, by recovering oocytes that may in any other case be naturally eradicated, we’re not affecting the fertility or ovarian reserve of the ladies who need to donate the oocytes.


In any case, it’s apparent that egg donation doesn’t preclude the donor from changing into pregnant. 

A puncture permits for the gathering of roughly ten oocytes. Even after menopause, a wholesome girl with no fertility points has a number of hundred eggs in reserve (even when they won’t mature naturally).